Article
Phase I trial of RV3-BB rotavirus vaccine: a human neonatal rotavirus vaccine.
Vaccine - 28 May 2013
Danchin M, Kirkwood C D, Lee K J, Bishop R F, Watts E, Justice F A, Clifford V, Cowley D, Buttery J P, Bines J E
Abstract excerpt
INTRODUCTION: RV3 is a human neonatal rotavirus strain (G3P[6]) that has been associated with asymptomatic neonatal infection and replicates well in the infant gut. RV3-BB rotavirus vaccine has been developed as a rotavirus vaccine candidate for administration at birth. METHODS: A single-centre, double-blind, randomised placebo-controlled Phase I study evaluated the safety and tolerability of a single oral dose...
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