Article
Mismatched dsRNA (ampligen) induces protection against genomic variants of the human immunodeficiency virus type 1 (HIV-1) in a multiplicity of target cells.
Antiviral research - 1 Jan 2000
Montefiori D C, Robinson W E, Mitchell W M
Abstract excerpt
Mismatched double-stranded RNA of the form r(I)n.r(C12-U)n (Ampligen) has been shown to be active against human immunodeficiency virus type 1 (HIV-1) using CEM and C3 cells as targets for infection by the highly similar HIV-1 isolates HTLV-IIIB and LAV (Montefiori, D.C. and Mitchell, W.M., 1987,...
Topics
- Antiviral Agents
- Cell Line
- Genetic Variation
- HIV
- Humans
- Macrophages
- Monocytes
- Poly I-C
- Poly U
- Polyribonucleotides
- RNA, Double-Stranded
- T-Lymphocytes, Helper-Inducer