Article
Placental miR-340 mediates vulnerability to activity based anorexia in mice.
Nature communications - 23 Apr 2018
Schroeder Mariana, Jakovcevski Mira, Polacheck Tamar, Drori Yonat, Luoni Alessia, Röh Simone, Zaugg Jonas, Ben-Dor Shifra, Albrecht Christiane, Chen Alon
Abstract excerpt
Anorexia nervosa (AN) is a devastating eating disorder characterized by self-starvation that mainly affects women. Its etiology is unknown, which impedes successful treatment options leading to a limited chance of full recovery. Here, we show that gestation is a vulnerable window that can influence the predisposition to AN. By screening placental microRNA expression of naive and prenatally stressed (PNS) fetuses...
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