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Article

Decreased whole-blood global DNA methylation is related to serum hormones in anorexia nervosa adolescents

29 Nov 2013

Abstract excerpt

OBJECTIVES: The one-carbon metabolism, also known as methionine-homocysteine cycle, governs the dynamics of DNA methylation, epigenetically regulating gene expression, and has been reported altered in anorexia nervosa (AN) adult patients. The aim of this study consisted in assessing whole-blood DNA methylation in adolescent AN patients, assessing its significance in relationship to clinical and hormonal...

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PMID: 24286295
DOI: 10.3109/15622975.2013.860467

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