Article
Laboratory and molecular surveillance of paediatric typhoidal Salmonella in Nepal: Antimicrobial resistance and implications for vaccine policy.
PLoS neglected tropical diseases - 1 Apr 2018
Britto Carl D, Dyson Zoe A, Duchene Sebastian, Carter Michael J, Gurung Meeru, Kelly Dominic F, Murdoch David R, Ansari Imran, Thorson Stephen, Shrestha Shrijana, Adhikari Neelam, Dougan Gordon, Holt Kathryn E, Pollard Andrew J
Abstract excerpt
BACKGROUND: Children are substantially affected by enteric fever in most settings with a high burden of the disease, including Nepal. However pathogen population structure and transmission dynamics are poorly delineated in young children, the proposed target group for immunization programs. Here we present whole genome sequencing and antimicrobial susceptibility data on 198 S. Typhi and 66 S. Paratyphi A isolated...
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