Article
Whole genome sequence analysis of Salmonella Typhi in Papua New Guinea reveals an established population of genotype 2.1.7 sensitive to antimicrobials.
PLoS neglected tropical diseases - 1 Mar 2022
Dyson Zoe Anne, Malau Elisheba, Horwood Paul F, Ford Rebecca, Siba Valentine, Yoannes Mition, Pomat William, Passey Megan, Judd Louise M, Ingle Danielle J, Williamson Deborah A, Dougan Gordon, Greenhill Andrew R, Holt Kathryn E
Abstract excerpt
BACKGROUND: Typhoid fever, a systemic infection caused by Salmonella enterica serovar Typhi, remains a considerable public health threat in impoverished regions within many low- and middle-income settings. However, we still lack a detailed understanding of the emergence, population structure, molecular mechanisms of antimicrobial resistance (AMR), and transmission dynamics of S. Typhi across many settings,...
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