Article
Clonal evolution through loss of chromosomes and subsequent polyploidization in chondrosarcoma.
PloS one - 1 Jan 2011
Olsson Linda, Paulsson Kajsa, Bovée Judith V M G, Nord Karolin H
Abstract excerpt
Near-haploid chromosome numbers have been found in less than 1% of cytogenetically reported tumors, but seem to be more common in certain neoplasms including the malignant cartilage-producing tumor chondrosarcoma. By a literature survey of published karyotypes from chondrosarcomas we could confirm that loss of chromosomes resulting in hyperhaploid-hypodiploid cells is common and that these cells may polyploidize....
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