Article
Chromosomal variability of human mesenchymal stem cells cultured under hypoxic conditions
21 Mar 2011
Abstract excerpt
Bone marrow derived human mesenchymal stem cells (hMSCs) have attracted great interest from both bench and clinical researchers because of their pluripotency and ease of expansion ex vivo. However, these cells do finally reach a senescent stage and lose their multipotent potential. Proliferation of these cells is limited up to the time of their senescence, which limits their supply, and they may accumulate...
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