Article
[Association of gene polymorphisms of matrix metalloproteinases with reproductive losses in the first trimester of pregnancy].
Genetika - 1 Aug 2016
Mashkina E V, Kovalenko K A, Marakhovskaya T A, Saraev K N, Belanova A A, Shkurat T P
Abstract excerpt
In the present study, the frequencies of genotypes and alleles of candidate genes with respect to polymorphisms associated with increased pregnancy loss in the first trimester of pregnancy, including MMP1–1607insG, MMP9 A–8202G, and TIMP1 С536T, were reported. The frequency of homozygotes for allele MMP9 A–8202 was increased by a factor of two among women with miscarriage in the first trimester compared to the...
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