Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-Wide Association Study on Adiponectin-Mediated Suppression of HDL-C Levels in Taiwanese Individuals Identifies Functional Haplotypes in CDH13.

Genes - 7 Oct 2021

Er Leay-Kiaw, Wu Semon, Cheng Tzuyu, Ko Yu-Lin, Teng Ming-Sheng

Abstract excerpt

CDH13 encodes T-cadherin, which is expressed in the vasculature and cardiac myocytes and is the receptor for hexameric and high-molecular-weight adiponectin. The CDH13 region is the most pivotal locus associated with adiponectin level. Mediation analysis is a method to explore the effect of a third variable, it is assumed that the magnitude of the relationship between the independent and dependent variables will...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adiponectin
Share to Asian People
Share to Biological Specimen Banks

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cadherins

Share to Cholesterol, HDL

Share to HEK293 Cells

Share to Myocytes, Cardiac

Share to Taiwan

Source

Open in PubMed Open full text

Identifiers

PMID: 34680977
DOI: 10.3390/genes12101582
PMCID: PMC8535967

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Association Study on Adiponectin-Mediated Suppression of HDL-C Levels in Taiwanese Individuals Identifies Functional Haplotypes in CDH13.PMID 34680977Read ↗

Association of CDH13 genotypes/haplotypes with circulating adiponectin levels, metabolic syndrome, and related metabolic phenotypes: the role of the suppression effect.Semantic proximity Read ↗

The Impact of CDH13 Polymorphism and Statin Administration on TG/HDL Ratio in Cardiovascular Patients.Semantic proximity Read ↗

CDH13 gene coding T-cadherin influences variations in plasma adiponectin levels in the Japanese population.Semantic proximity Read ↗

CDH13 promoter SNPs with pleiotropic effect on cardiometabolic parameters represent methylation QTLs.Semantic proximity Read ↗

A genome-wide association study reveals a quantitative trait locus of adiponectin on CDH13 that predicts cardiometabolic outcomes.Semantic proximity Read ↗

CDH13 Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass.Semantic proximity Read ↗

An interplay of non-coding RNAs regulates CDH13 expression and affects endothelial function and coronary artery disease riskSemantic proximity Read ↗

Genetic variation in CDH13 is associated with lower plasma adiponectin levels but greater adiponectin sensitivity in East Asian populations.Semantic proximity Read ↗

Association between CDH13 variants and cardiometabolic and vascular phenotypes in a Korean population.Semantic proximity Read ↗

Differential Associations between CDH13 Genotypes, Adiponectin Levels, and Circulating Levels of Cellular Adhesive Molecules.Semantic proximity Read ↗

Adiponectin concentrations: a genome-wide association study.Semantic proximity Read ↗

[Single Nucleotide Polymorphisms in T-Cadherin Gene (CDH13) Have Cumulative Effect on Body Mass in Patients With Ischemic Heart Disease].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.