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Article

CD133 Promotes Adhesion to the Ovarian Cancer Metastatic Niche

1 Jan 2018

Abstract excerpt

Cancer stem cells (CSCs) are an attractive therapeutic target due to their predicted role in both metastasis and chemoresistance. One of the most commonly agreed on markers for ovarian CSCs is the cell surface protein CD133. CD133+ ovarian CSCs have increased tumorigenicity, resistance to chemotherapy, and increased metastasis. Therefore, we were interested in defining how CD133 is regulated and whether it has a...

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PMID: 29662326
DOI: 10.1177/1179064418767882

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