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Article

Modulation of epithelial homeostasis by HPV using Notch and Wnt

13 Nov 2024

Abstract excerpt

Highly conserved signalling pathways such as Notch and Wnt are essential in the regulation of differentiation and proliferation processes during adult tissue homeostasis. Human papillomaviruses (HPVs) have evolved with humans to manipulate these signalling pathways to establish a basal reservoir of infected cells by limiting HPV-infected keratinocyte differentiation whilst ensuring that differentiating cells are...

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PMID: 39542216
DOI: 10.1016/j.tvr.2024.200297

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