Article
Genetic factors in drug metabolism.
American family physician - 1 Jun 2008
Belle Donna J, Singh Harleen
Abstract excerpt
Patients vary widely in their response to drugs. Having an understanding of the pharmacokinetic and pharmacodynamic properties of various medications is importantwhen assessing ethnic differences in drug response. Genetic factors can account for 20 to 95 percent of patient variability. Genetic polymorphisms for many drug-metabolizing enzymes and drug targets (e.g., receptors) have been identified. Although...
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