Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular engineering of the salicylate-inducible transcription factor Sal7AR for orthogonal and high gene expression in Escherichia coli.

PloS one - 1 Jan 2018

Miyazaki Kentaro

Abstract excerpt

I have previously identified a metagenomic fragment (~4 kb) containing the salicylate (2-hydroxybenzoate)-responsive transcriptional regulator Sal7AR. Taking advantage of the inert nature of salicylate to common genetic switches used in Escherichia coli, here I developed a salicylate-inducible high expression system in E. coli. I first applied a deletion analysis to the metagenomic fragment to identify the core...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Escherichia coli
Share to Gene Expression

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Mutation

Share to Promoter Regions, Genetic

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 29641575
DOI: 10.1371/journal.pone.0194090
PMCID: PMC5894983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular engineering of the salicylate-inducible transcription factor Sal7AR for orthogonal and high gene expression in Escherichia coli.PMID 29641575Read ↗

Reverse engineering of an aspirin-responsive regulator in bacteriaSemantic proximity Read ↗

Using transcription machinery engineering to elicit complex cellular phenotypes.Semantic proximity Read ↗

Chromosomally located gene fusions constructed in Acinetobacter sp. ADP1 for the detection of salicylate.Semantic proximity Read ↗

A regulatory toolkit of arabinose-inducible artificial transcription factors for Gram-negative bacteriaSemantic proximity Read ↗

Strategy for directing combinatorial genome engineering in Escherichia coli.Semantic proximity Read ↗

Construction of Escherichia coli gene expression level perturbation collection.Semantic proximity Read ↗

Plant protoplast-based assay to screen for salicylic acid response-modulating bacteriaSemantic proximity Read ↗

Use of a riboswitch-controlled conditional hypomorphic mutation to uncover a role for the essential csrA gene in bacterial autoaggregation.Semantic proximity Read ↗

Systematic insertional mutagenesis of a streptomycete genome: a link between osmoadaptation and antibiotic production.Semantic proximity Read ↗

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial SpeciesSemantic proximity Read ↗

Modular, inducible, and titratable expression systems for <i>Escherichia coli</i> and <i>Acinetobacter baumannii</i>Semantic proximity Read ↗

Global strain engineering by mutant transcription factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.