Age-dependent modulation of bone metabolism in zebrafish scales as new model of male osteoporosis in lower vertebrates

Abstract excerpt

After middle age, in human bone, the resorption usually exceeds formation resulting in bone loss and increased risk of fractures in the aged population. Only few in vivo models in higher vertebrates are available for pathogenic and therapeutic studies about bone aging. Among these, male Danio rerio (zebrafish) can be successfully used as low vertebrate model to study degenerative alterations that affect the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone health and osteoporosis research
• Share to Bone Metabolism and Diseases
• Share to Zebrafish Biomedical Research Applications