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Article

Genetic diversification of chemokine CXCL16 and its receptor CXCR6 in primates.

Developmental and comparative immunology - 1 Aug 2018

Xu Feifei, He Dan, Liu Jiabin, Ni Qingyong, Lyu Yongqing, Xiong Shiqiu, Li Yan

Abstract excerpt

Chemokine CXCL16 and its receptor CXCR6 are associated with a series of physiological and pathological processes in cooperative and stand-alone fashions. To shed insight into their versatile nature, we studied genetic variations of CXCL16 and CXCR6 in primates. Evolutionary analyses revealed that these genes underwent a similar evolutionary fate. Both genes experienced adaptive diversification with the...

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Identifiers

PMID: 29635005
DOI: 10.1016/j.dci.2018.04.005

Genes

CXCL16
CXCR6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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