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Article

Down-Regulated miR-125a-5p Promotes the Reprogramming of Glucose Metabolism and Cell Malignancy by Increasing Levels of CD147 in Thyroid Cancer

29 Mar 2018

Abstract excerpt

BACKGROUND: CD147 contributes to increased aerobic glycolysis through which it promotes tumor growth. Accumulating evidence suggests that CD147 exerts a variety of functions in thyroid cancer (TC) progression but the molecular mechanisms and therapeutic value of CD147 remain unclear. METHODS: CD147 levels in TC tissues were analyzed to assess its relationship with prognosis and disease progression. A microRNA...

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PMID: 29634399
DOI: 10.1089/thy.2017.0401

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