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Article

Down-regulation of 14q32-encoded miRNAs and tumor suppressor role for miR-654-3p in papillary thyroid cancer.

Oncotarget - 7 Feb 2017

Geraldo Murilo Vieira, Nakaya Helder Imoto, Kimura Edna Teruko

Abstract excerpt

Papillary thyroid carcinoma (PTC) is the most prevalent malignant neoplasia of the thyroid gland. A fraction of PTC cases show loss of differentiation and aggressive behavior, with radioiodine therapy resistance and metastasis. Although microRNAs (miRNAs) emerged as promising molecular markers for PTC, their role in the loss of differentiation observed during PTC progression remains to be fully understood. We...

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Share to Carcinoma, Papillary
Share to Chromosomes, Human, Pair 14

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Epithelial-Mesenchymal Transition

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Identifiers

PMID: 28030816
DOI: 10.18632/oncotarget.14162
PMCID: PMC5354756

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