Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RNF4 regulates zebrafish granulopoiesis through the DNMT1-C/EBPα axis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Sept 2018

Wang Luxiang, Liu Xiaohui, Wang Haihong, Yuan Hao, Chen Saijuan, Chen Zhu, de The Hugues, Zhou Jun, Zhu Jun

Abstract excerpt

RING finger protein 4 (RNF4) is a multifunctional small ubiquitin-related modifier (SUMO)-targeted ubiquitin E3 ligase (STUbL) ubiquitously expressed in all tissues, and which mainly participates in DNA repair and in chromatin and transcriptional regulation. Although RNF4 has been implicated in hematopoietic disorders, its ontogenic role during hematopoietic development remains undiscovered. We generated a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CCAAT-Enhancer-Binding Protein-alpha
Share to DNA (Cytosine-5-)-Methyltransferase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to Hematopoiesis

Share to SUMO-1 Protein

Share to Sumoylation

Share to Zebrafish

Share to Zebrafish Proteins

Source

Identifiers

PMID: 29634367
DOI: 10.1096/fj.201701450RR

Genes

RNF4
DNMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RNF4 regulates zebrafish granulopoiesis through the DNMT1-C/EBPα axis.PMID 29634367Read ↗

Cebpα is essential for the embryonic myeloid progenitor and neutrophil maintenance in zebrafish.Semantic proximity Read ↗

Gata2a maintains <i>cebpa</i> and <i>npm1a</i> in haematopoietic stem cells to sustain lineage differentiation and genome stabilitySemantic proximity Read ↗

UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid DevelopmentSemantic proximity Read ↗

Zfp263 is a transcriptional checkpoint of neutrophil developmentSemantic proximity Read ↗

<i>rapunzel5</i> is necessary for normal hematopoietic development in zebrafishSemantic proximity Read ↗

Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis.Semantic proximity Read ↗

LEF-1 is a decisive transcription factor in neutrophil granulopoiesis.Semantic proximity Read ↗

SUMO1-activating enzyme subunit 1 is essential for the survival of hematopoietic stem/progenitor cells in zebrafish.Semantic proximity Read ↗

Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6.Semantic proximity Read ↗

GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia.Semantic proximity Read ↗

A zebrafish model for HAX1-associated congenital neutropenia.Semantic proximity Read ↗

Gfi-1 Oncoproteins in HematopoiesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.