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Article

Ift25 is not a cystic kidney disease gene but is required for early steps of kidney development.

Mechanisms of development - 1 Jun 2018

Desai Paurav B, San Agustin Jovenal T, Stuck Michael W, Jonassen Julie A, Bates Carlton M, Pazour Gregory J

Abstract excerpt

Eukaryotic cilia are assembled by intraflagellar transport (IFT) where large protein complexes called IFT particles move ciliary components from the cell body to the cilium. Defects in most IFT particle proteins disrupt ciliary assembly and cause mid gestational lethality in the mouse. IFT25 and IFT27 are unusual components of IFT-B in that they are not required for ciliary assembly and mutant mice survive to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Kidney

Share to Kidney Diseases, Cystic

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Source

Open in PubMed Open full text

Identifiers

PMID: 29626631
DOI: 10.1016/j.mod.2018.04.001
PMCID: PMC5972074

Genes

IFT25
IFT27

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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