Article
Genome-wide association study and meta-analysis identify loci associated with ventricular and supraventricular ectopy.
Scientific reports - 4 Apr 2018
Napier Melanie D, Franceschini Nora, Gondalia Rahul, Stewart James D, Méndez-Giráldez Raúl, Sitlani Colleen M, Seyerle Amanda A, Highland Heather M, Li Yun, Wilhelmsen Kirk C, Yan Song, Duan Qing, Roach Jeffrey, Yao Jie, Guo Xiuqing, Taylor Kent D, Heckbert Susan R, Rotter Jerome I, North Kari E, Reiner Alexander P, Zhang Zhu-Ming, Tinker Lesley F, Liao Duanping, Laurie Cathy C, Gogarten Stephanie M, Lin Henry J, Brody Jennifer A, Bartz Traci M, Psaty Bruce M, Sotoodehnia Nona, Soliman Elsayed Z, Avery Christy L, Whitsel Eric A
Abstract excerpt
The genetic basis of supraventricular and ventricular ectopy (SVE, VE) remains largely uncharacterized, despite established genetic mechanisms of arrhythmogenesis. To identify novel genetic variants associated with SVE/VE in ancestrally diverse human populations, we conducted a genome-wide association study of electrocardiographically identified SVE and VE in five cohorts including approximately 43,000...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.