Article
Effects of a Polymorphism in the Promoter Region of the Follicle-Stimulating Hormone Subunit Beta ( FSHB ) Gene on Female Reproductive Outcomes
26 Dec 2018
Abstract excerpt
BACKGROUND: Follicle-stimulating hormone (FSH) is essential to the hypothalamic-pituitary-gonadal axis, playing a key role in human reproduction. It is a heterodimer comprised of a hormone-specific β-chain (FSH-β) that is associated with an α-chain. It exerts its biological activities by binding to the FSH receptor (FSHR). The β-subunit, which is encoded by the FSHB gene, is responsible for ensuring binding...
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