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Characterization of Sex-Based Dna Methylation Signatures in the Airways During Early Life

29 Mar 2018

Abstract excerpt

Human respiratory conditions are largely influenced by the individual's sex resulting in overall higher risk for males. Sex-based respiratory differences are present at birth suggesting a strong genetic component. Our objective was to characterize early life sex-based genomic signatures determined by variable X-chromosome methylation in the airways. We compared male versus female genome-wide DNA methylation in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29615635
DOI: 10.1038/s41598-018-23063-5

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