Article
An update on epigenetics and childhood respiratory diseases.
Paediatric respiratory reviews - 1 Dec 2014
Gruzieva Olena, Merid Simon Kebede, Melén Erik
Abstract excerpt
Epigenetic mechanisms, defined as changes in phenotype or gene expression caused by mechanisms other than changes in the underlying DNA sequence, have been proposed to constitute a link between genetic and environmental factors that affect complex diseases. Recent studies show that DNA methylation, one of the key epigenetic mechanisms, is altered in children exposed to air pollutants and environmental tobacco...
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