Article
Are PR3 positive and MPO positive GPA the same disease?
International journal of rheumatic diseases - 1 Jan 2019
Fordham Sarah, Mukhtyar Chetan
Abstract excerpt
Granulomatosis with Polyangiitis is a necrotising systemic vasculitis predominantly affecting small and medium sized vessels. It is predominantly associated with antibodies directed against proteinase 3, but a small number of individuals with this disease have antibodies directed against myeloperoxidase. The premise of this paper is to explore the possibility that these two serotypes maybe two separate diseases....
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