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Article

Pathogenesis of ANCA-associated vasculitis: new possibilities for intervention.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Dec 2013

Kallenberg Cees G M, Stegeman Coen A, Abdulahad Wayel H, Heeringa Peter

Abstract excerpt

The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) comprise granulomatosis with polyangiitis (GPA), primarily associated with antibodies to proteinase 3 (PR3-ANCA); microscopic polyangiitis (MPA); and eosinophilic granulomatosis with polyangiitis (EGPA), both principally associated with antibodies to myeloperoxidase (MPO-ANCA). Genetic and environmental factors are involved in their...

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Identifiers

PMID: 23810690
DOI: 10.1053/j.ajkd.2013.05.009

Genes

MPO

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