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Article

High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival.

PLoS genetics - 1 Apr 2018

Rubin Benjamin E, Huynh TuAnh Ngoc, Welkie David G, Diamond Spencer, Simkovsky Ryan, Pierce Emily C, Taton Arnaud, Lowe Laura C, Lee Jenny J, Rifkin Scott A, Woodward Joshua J, Golden Susan S

Abstract excerpt

The broadly conserved signaling nucleotide cyclic di-adenosine monophosphate (c-di-AMP) is essential for viability in most bacteria where it has been studied. However, characterization of the cellular functions and metabolism of c-di-AMP has largely been confined to the class Bacilli, limiting our functional understanding of the molecule among diverse phyla. We identified the cyclase responsible for c-di-AMP...

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Identifiers

PMID: 29608558
DOI: 10.1371/journal.pgen.1007301
PMCID: PMC5897029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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