Article
Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montréal-Ottawa New Emerging Team, and Complications Associated with Obesity.
BMC medical genetics - 11 Aug 2016
Rajkumar Abishankari, Lamothe Gilles, Bolongo Pierrette, Harper Mary-Ellen, Adamo Kristi, Doucet Éric, Rabasa-Lhoret Remi, Prud'homme Denis, Tesson Frédérique
Abstract excerpt
BACKGROUND: Genetic studies on Acyl-CoA Synthetase Long-Chain 5 (ACSL5) demonstrate an association between rs2419621 genotype and rate of weight loss in women with obesity in response to caloric restriction. Our objectives were to (1) confirm results in two different populations of women with overweight and obesity (2) study rs2419621's influence on body composition parameters of women with overweight and obesity...
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