Article
The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.
Molecular nutrition & food research - 1 Mar 2006
Lindner Inka, Rubin Diana, Helwig Ulf, Nitz Inke, Hampe Jochen, Schreiber Stefan, Schrezenmeir Jürgen, Döring Frank
Abstract excerpt
Enzymes of the medium-chain acyl-CoA synthetase (MACS) family catalyze the ligation of medium chain fatty acids with CoA to produce medium-chain-acyl-CoA. At least four members of the MACS gene family are clustered on human chromosome 16p12. Association studies in the Japanese Suita cohort of MACS polymorphisms and various phenotypes revealed the contribution of the Leu513Ser polymorphism in MACS2 to multiple...
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