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Article

Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents.

Journal of psychiatric research - 1 Jul 2018

Ciuculete Diana M, Boström Adrian E, Tuunainen Anna-Kaisa, Sohrabi Farah, Kular Lara, Jagodic Maja, Voisin Sarah, Mwinyi Jessica, Schiöth Helgi B

Abstract excerpt

Generalized anxiety disorder (GAD) is highly prevalent among adolescents. An early detection of individuals at risk may prevent later psychiatric condition. Genome-wide studies investigating single nucleotide polymorphisms (SNPs) concluded that a focus on epigenetic mechanisms, which mediate the impact of environmental factors, could more efficiently help the understanding of GAD pathogenesis. We investigated the...

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PMID: 29604450
DOI: 10.1016/j.jpsychires.2018.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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