Article
Newborn genome-wide DNA methylation in association with pregnancy anxiety reveals a potential role for GABBR1.
Clinical epigenetics - 1 Jan 2017
Vangeel Elise Beau, Pishva Ehsan, Hompes Titia, van den Hove Daniel, Lambrechts Diether, Allegaert Karel, Freson Kathleen, Izzi Benedetta, Claes Stephan
Abstract excerpt
BACKGROUND: There is increasing evidence for the role of prenatal stress in shaping offspring DNA methylation and disease susceptibility. In the current study, we aimed to identify genes and pathways associated with pregnancy anxiety using a genome-wide DNA methylation approach. METHODS: We selected 22 versus 23 newborns from our Prenatal Early Life Stress (PELS) cohort, exposed to the lowest or highest degree of...
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