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Article

Increased centrosome number in BRCA-related breast cancer specimens determined by immunofluorescence analysis.

Cancer science - 1 Jun 2018

Watanabe Gou, Chiba Natsuko, Nomizu Tadashi, Furuta Akihiko, Sato Kaolu, Miyashita Minoru, Tada Hiroshi, Suzuki Akihiko, Ohuchi Noriaki, Ishida Takanori

Abstract excerpt

BRCA-related breast carcinoma can be prevented through prophylactic surgery and an intensive follow-up regimen. However, BRCA genetic tests cannot be routinely performed, and some BRCA mutations could not be defined as deleterious mutations or normal variants. Therefore, an easy functional assay of BRCA will be useful to evaluate BRCA status. As it has been reported that BRCA functions in the regulation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29601120
DOI: 10.1111/cas.13595
PMCID: PMC5989840

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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