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Article

Molecularly barcoded Zika virus libraries to probe in vivo evolutionary dynamics

28 Mar 2018

Abstract excerpt

Defining the complex dynamics of Zika virus (ZIKV) infection in pregnancy and during transmission between vertebrate hosts and mosquito vectors is critical for a thorough understanding of viral transmission, pathogenesis, immune evasion, and potential reservoir establishment. Within-host viral diversity in ZIKV infection is low, which makes it difficult to evaluate infection dynamics. To overcome this biological...

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PMID: 29590202
DOI: 10.1371/journal.ppat.1006964

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