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Article

Using barcoded Zika virus to assess virus population structure in vitro and in Aedes aegypti mosquitoes.

Virology - 1 Aug 2018

Weger-Lucarelli James, Garcia Selene M, Rückert Claudia, Byas Alex, O'Connor Shelby L, Aliota Matthew T, Friedrich Thomas C, O'Connor David H, Ebel Gregory D

Abstract excerpt

Arboviruses such as Zika virus (ZIKV, Flaviviridae; Flavivirus) must replicate in both mammalian and insect hosts possessing strong immune defenses. Accordingly, transmission between and replication within hosts involves genetic bottlenecks, during which viral population size and genetic diversity may be significantly reduced. To help quantify these bottlenecks and their effects, we constructed 4 "barcoded" ZIKV...

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Identifiers

PMID: 29935423
DOI: 10.1016/j.virol.2018.06.004
PMCID: PMC6309320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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