Article
Sarcomatoid carcinoma represents a complete phenotype with various pathways of epithelial mesenchymal transition.
Journal of clinical pathology - 1 Jul 2013
Sung Chang Ohk, Choi Hannah, Lee Keun-Woo, Kim Seok-Hyung
Abstract excerpt
AIMS: Sarcomatoid carcinoma (SC) is considered to be a result of the sarcomatoid change of epithelial carcinoma. However, epithelial-mesenchymal transition (EMT) in SC has been insufficiently studied. METHODS: We evaluated the expression patterns of EMT-related phenotypic markers with transcription factors in 27 SCs originating from various organs, and we investigated the phenotypic characteristics of SCs...
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