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Article

Telomerase reverse transcriptase promoter mutations and solar elastosis in cutaneous melanoma.

Melanoma research - 1 Oct 2018

Lade-Keller Johanne, Yuusufi Sakineh, Riber-Hansen Rikke, Steiniche Torben, Stougaard Magnus

Abstract excerpt

The aims of this study were to assess the prognostic potential of solar elastosis grading and telomerase reverse transcriptase (TERT) promoter mutations (TERTp) in melanoma and to evaluate whether an association between solar elastosis and TERTp exists. Solar elastosis in the dermis was evaluated in hematoxylin and eosin-stained whole slides from 486 malignant melanomas. Pyrosequencing was used to detect TERTp in...

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Source

Identifiers

PMID: 29570169
DOI: 10.1097/CMR.0000000000000446

Genes

BRAF
TERT

Variants

Provenance

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