Article
Zebrafish as a model system to study heritable skin diseases.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2013
Li Qiaoli, Uitto Jouni
Abstract excerpt
Heritable skin diseases represent a broad spectrum of clinical manifestations due to mutations in ∼500 different genes. A number of model systems have been developed to advance our understanding of the pathomechanisms of genodermatoses. Zebrafish (Danio rerio), a freshwater vertebrate, has a well-characterized genome, the expression of which can be easily manipulated. The larvae develop rapidly, with all major...
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