Effects of Deficient Glycosylation and Deglycosylation on Sperm Condition in Zebrafish ( <i>Danio rerio</i> )

Abstract excerpt

Congenital disorders of glycosylation and deglycosylation are rare, serious, and lethal disorders afflicting humans. CDGs and CDDGs result in loss of function enzymes which fail to build or break down oligosaccharides on proteins. This can produce protein aggregates and, in turn, reactive oxygen species that harm the cell eventually leading to autophagy and apoptosis. Because sperm contain high concentrations of p...

Topics

Open a Topic to create a Post that cites this publication.

• Base Sequence
• Congenital Disorders of Glycosylation
• Dietary Supplements
• Disease Models, Animal
• Gene Knockdown Techniques
• Mannose
• Morpholinos
• Zebrafish

Identifiers and source

Literature Corpus work

236c064e-fb63-524e-8ebb-05c6ae1df578

DOI

10.64898/2026.07.01.735899