Article
Mutations at key pore-lining positions differentiate the water permeability of fish lens aquaporin from other vertebrates.
FEBS letters - 1 Dec 2010
Calvanese Luisa, Pellegrini-Calace Marialuisa, Oliva Romina
Abstract excerpt
Aquaporin-0 (AQP0) is the major integral membrane protein of lens fiber cell and helps to maintain lens transparency by mediating inter-cell adhesion. To shed light on the unexpected higher water transport efficiency of killifish AQP0 as compared to mammalian orthologues, we performed a comparati...
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