Article
Novel compound heterozygous mutations in the PARK2 gene identified in a Chinese pedigree with early-onset Parkinson's disease.
Brain and behavior - 1 Jan 2018
Shi Yingying, Kawakami Hideshi, Zang Weizhou, Li Gang, Zhang Jiewen, Xu Changshui
Abstract excerpt
Objects: To capture point mutations and short insertions/deletions in 49 previously reported genes associated with Parkinson's disease (PD) in a Chinese pedigree with early-onset Parkinson's disease (EOPD)-affected individuals. Methods: Clinical examinations and genomic analysis were performed on 21 subjects belonging to three generations of a Chinese family. Target region capture and high-throughput sequencing...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.