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Article

Composition of the immune microenvironment differs between carcinomas metastatic to the lungs and primary lung carcinomas.

Annals of diagnostic pathology - 1 Apr 2018

Senarathne Wijendra, Vranic Semir, Xiu Joanne, Rose Inga, Gates Peggy, Gatalica Zoran

Abstract excerpt

Lungs are among the most common sites for development of both primary and metastatic carcinomas. Tumor cells expression (TC) of PD-L1 is an important predictor of the of response to immune check-point inhibition in NSCLC, while the composition of the immune cells (IC) in the tumor microenvironment including PD-L1+ cells is believed to predict responses in tumors of some other primary sites. Total mutational load...

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PMID: 29566951
DOI: 10.1016/j.anndiagpath.2017.12.004

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