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Article

Heterogeneity in PD-L1 expression between primary and metastatic lymph nodes: a predictor of EGFR-TKI therapy response in non-small cell lung cancer.

Respiratory research - 5 Jun 2024

Hu Yaohua, Zhang Yidan, Lu You, Xu Yingqi, Xu Jianlin, Zhong Hua, Cheng Lei, Zhong Runbo

Abstract excerpt

BACKGROUND: There is inconclusive evidence to suggest that the expression of programmed cell death ligand 1 (PD-L1) is a putative predictor of response to EGFR-TKI therapy in advanced EGFR-mutant non-small cell lung cancer (NSCLC). We evaluated the heterogeneity in PD-L1 expression in the primary lung site and metastatic lymph nodes to analyze the association between PD-L1 expression and response for patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38840238
DOI: 10.1186/s12931-024-02858-3
PMCID: PMC11151486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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