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Article

Phosphoinositide-3-Kinase Signaling in Human Natural Killer Cells: New Insights from Primary Immunodeficiency.

Frontiers in immunology - 1 Jan 2018

Mace Emily M

Abstract excerpt

Human natural killer (NK) cells play a critical role in the control of viral infections and malignancy. Their importance in human health and disease is illustrated by severe viral infections in patients with primary immunodeficiencies that affect NK cell function and/or development. The recent identification of patients with phosphoinositide-3-kinase (PI3K)-signaling pathway mutations that can cause primary...

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Share to Cell Differentiation
Share to Cell Movement
Share to Cytotoxicity, Immunologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme Activation

Share to Immunologic Deficiency Syndromes

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Share to Phosphatidylinositol 3-Kinases

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Source

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Identifiers

PMID: 29563913
DOI: 10.3389/fimmu.2018.00445
PMCID: PMC5845875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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