Article
Genetic polymorphisms of TP53 Arg72Pro and Pro47Ser among Egyptian patients with colorectal carcinoma.
Archives of physiology and biochemistry - 1 Jul 2019
Elsaid Afaf, Zahran Rasha, Elshazli Rami, El-Sayed Ahmed, Abou Samra Marwa, El-Tarapely Fatma, Abdel-Malak Camelia
Abstract excerpt
BACKGROUND: Previous reports demonstrated the role of TP53 gene polymorphisms with CRC risk among several ethnic populations. The purpose of this study is to assess the association of the TP53 Arg72Pro and Pro47Ser variants with CRC risk among Egyptian patients. SUBJECTS AND METHODS: This work was conducted on 120 unrelated CRC Egyptian patients who were compared to 140 healthy controls. DNA was genotyped for...
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