TP53 Gene Pro72Arg (rs1042522) Single Nucleotide Polymorphism as Not a Risk Factor for Colorectal Cancer in the Iranian Azari Population

doi:10.22034/APJCP.2017.18.12.3423

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TP53 Gene Pro72Arg (rs1042522) Single Nucleotide Polymorphism as Not a Risk Factor for Colorectal Cancer in the Iranian Azari Population

Asian Pacific journal of cancer prevention : APJCP - 29 Dec 2017

Asadi Milad, Shanehbandi Dariush, Zarintan Armin, Pedram Negar, Baradaran Behzad, Zafari Venus, Shirmohamadi Masoud, Hashemzadeh Shahriyar

Abstract excerpt

Background: The p53 protein participates critically in several cellular functions such as cell growth and DNA repair. Polymorphisms in the TP53 locus have repeatedly been implicated in the pathogenesis of cancers all over the world. Over 200 single nucleotide polymorphisms (SNPs) have been characterized, but one well-known example at at codon 72, Pro72Arg (rs1042522), has the displayed inconsistent results with...

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PMID: 29286614
DOI: 10.22034/APJCP.2017.18.12.3423
PMCID: PMC5980905

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