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Article

Differential expression pattern of co-inhibitory molecules on CD4+ T cells in uncomplicated versus complicated malaria

13 Mar 2018

Abstract excerpt

Abstract The immune response of malaria patients is a main factor influencing the clinical severity of malaria. A tight regulation of the CD4+ T cell response or the induction of tolerance have been proposed to contribute to protection from severe or clinical disease. We therefore compared the CD4+ T cell phenotypes of Ghanaian children with complicated malaria, uncomplicated malaria, asymptomatic Plasmodium...

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PMID: 29555909
DOI: 10.1038/s41598-018-22659-1

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