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Weighted Gene Co-expression Network Analysis Identifies a Cancer-Associated Fibroblasts Signature for Predicting Prognosis and Immunotherapeutic Responses in Skin Cutaneous Melanoma

2023-09-12

Abstract excerpt

<h4>Objective: </h4> Cancer-associated fibroblasts (CAFs) are the most prominent cellular component in the stroma of skin cutaneous melanoma (SKCM). The aim of this study was to explore the CAFs-related genes and to develop a CAFs-related model to predict the prognosis and immunotherapeutic efficacy of SKCM. <h4>Method:</h4> We collected mRNA expression and clinical information for 449 SKCM patients from the TCGA...

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Literature Corpus work
9abe6058-3fc6-5eae-bd11-cab320a55a2f
DOI
10.21203/rs.3.rs-3330660/v1
Open publication

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