Article
The molecular landscape of synchronous colorectal cancer reveals genetic heterogeneity.
Carcinogenesis - 3 May 2018
Wang Xiangfeng, Fang Hu, Cheng Yong, Li Lin, Sun Xiaohui, Fu Tao, Huang Peide, Zhang Anping, Feng Zhimin, Li Chunxue, Huang Xuanlin, Li Guangyan, Du Peina, Yang Huanming, Fang Xiaodong, Li Fan, Gao Qiang, Liu Baohua
Abstract excerpt
Synchronous colorectal cancers (syCRCs), which present two or more lesions at diagnosis, are rare and pose a great challenge for clinical management. Although some predisposing factors associated with syCRCs have been studied with limited accession, the full repertoire of genomic events among the lesions within an individual and the causes of syCRCs remain unclear. We performed whole-exome sequencing of 40...
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