Article
Polymorphisms in the Egl nine homolog 3 (EGLN3) and Peroxisome proliferator activated receptor-alpha (PPARα) genes and their correlation with hypoxia adaptation in Tibetan chickens.
PloS one - 1 Jan 2018
Zhong ChengLin, Li SiChen, Li JingJing, Li FengPeng, Ran MingXia, Qiu LingYun, Li DiYan, Zhu Qing, Wang Yan, Yin HuaDong, Shu Gang, Yang Chaowu, Zhao XiaoLing
Abstract excerpt
Peroxisome proliferator activated receptor-alpha (PPARα) and Egl nine homolog 3 (EGLN3) play critical roles in facilitating the adaptation to a hypoxic environment. However, the relationship between EGLN3 and PPARα variants and hypoxic adaptation remains poorly understood in Tibetan chickens. To better understand the effects of genetic variation, we sequenced exons of PPARα and EGLN3 in 138 Lowland chickens (LC)...
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