Article
Complex epidermal growth factor receptor mutations and their responses to tyrosine kinase inhibitors in previously untreated advanced lung adenocarcinomas.
Cancer - 1 Jun 2018
Zhang Bo, Wang Shuyuan, Qian Jie, Yang Wenjia, Qian Fangfei, Lu Jun, Zhang Yanwei, Qiao Rong, Han Baohui
Abstract excerpt
BACKGROUND: Two or more different epidermal growth factor receptor (EGFR) mutations can be detected within a single tumor sample, which represents complex mutations. However, the frequency and efficacy of tyrosine kinase inhibitor (TKI) treatments for patients harboring these mutations are unknown. METHODS: From January 2011 to January 2017, patients diagnosed with EGFR mutations were screened. The effectiveness...
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